Advanced symptoms of Epidermolytic Hyperkeratosis

The scale formation stage of the advanced epidermolytic Hyperkeratosis is one of the most prominent feature of the diseases. The scale can be described as “ corrugated cardboard like design” The palms and soles often become the most affected parts of advanced epidermolytic hyperkeratosis as they become very thickened , almost looking like leprosy, the colours of the palm often turn to orange-like or pale yellow. Based on the scale formation, epidermolytic hyperkeratosis can be classified into 2- the NPS and the PS . The NPS epidermolytic hyperkeratosis is the one that excludes severe palm and soles hyperkeratosis while the PS  comes with severe soles and palm hyperkeratosis.

The advanced form of the NPS type of epidermolytic hyperkeratosis can also come with some other features. For instance , a generalized skin distribution of the scales can occur and brown scales often form rather than the hystrix formation . A thin white scale is often prominent with the NPS type of epidermolytic hyperkeratosis. No gait abnormalities occur here but the thin white scale becomes more pronounced especially at the trunk.

The PS epidermolitic hyperkeratosis is often characterized by some smooth palmo-plantar which often comes with some smooth surfaces but no digital contractures at the surface of the hyperkeratosis site. A tan scale and generalized  plus neonatal blistering and no gait abnormalities also characterized the PS epidermolytic hyperkeratosis.  One of the very rare cases that has been reported on Epidermolytic Hyperkeratosis is the formation of some rickety which has been traced to lack of Vitamin D in such patients.

Patients with generalized Epidermolytic Hyperkeratosis are born to parents which have suffered the infection at one time or the other. Generalized redness, and generally dark scales that forms parallel to each other are some of the most pronounced appearances of Epidermolytic hyperkeratosis. Other common features of the infection include; ridges forming at the large joints of the skin, and the skin becomes more fragile and blisters follow the trauma that accompany the blisters. The hair around the infected parts often become sparse .

Analysis of the cellular DNA is one of the ways of ascertaining the presence of epidermolytic hyper-keratosis. This test can be conducted at birth or after birth.  Fortunately, people who suffer from epidermolytic hyperkeratosis should expect that the condition becomes better as they age. There are several forms of treatments which can aid the full recovery of an individual suffering from this infection.

Further Hyperkeratosis ReadingHyperkeratosis Reading:

Actinic Keratosis – Seborrheic Keratosis – Skin Eczema

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Ag3derm skin cream – Seborrheic Keratosis – Actinic Keratosis – Keratosis Treatment